AWS Helps Pfizer Accelerate Drug Development and Clinical Manufacturing

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AWS Works With Pfizer To Support Faster Innovation And Improved Clinical Manufacturing Operations To Help Develop The Therapies Of Tomorrow

Today, Amazon Web Services, Inc. (AWS), a company of Amazon.com, Inc. (NASDAQ: AMZN), announced that it is working with Pfizer to create innovative cloud-based solutions with the potential to improve the way new drugs are developed, manufactured and distributed to be tested in clinical trials. The companies are exploring these advancements as part of their newly formed Pfizer Amazon Collaboration Team (PACT) initiative, which applies AWS capabilities in analytics, machine learning, compute, storage, security, and warehousing from data in the cloud at the Pfizer lab, clinical manufacturing and clinical supply chain. efforts. For example, AWS helps Pfizer improve its continuous clinical manufacturing processes by incorporating predictive maintenance capabilities built with AWS machine learning services like Amazon Lookout for Equipment. analyzing sensor data). As a result, Pfizer can maximize the availability of equipment such as centrifuges, agitators, sprayers, coaters and air handlers used in the manufacture of clinical drugs. The overall goal of this collaboration is to help Pfizer produce new drugs faster and more reliably and assess their potential health benefits for patients.

“Our customers in the life sciences industry are increasingly looking for opportunities to develop their expertise, knowledge and secure access to the right information, at the right time, with the aim of reducing the time and costs of developing drugs and clinical trials, ”said Kathrin Renz, vice president of business development and industries at Amazon Web Services, Inc.“ The breadth and depth of AWS’s cloud capabilities help Pfizer teams use new secure research methods to optimize drug development and clinical manufacturing processes. The past two years have reinforced for the world how important speed and agility are at every stage of the research, development and clinical manufacturing cycle when lives are on the line. We are proud to work with Pfizer and to make available our deep domain expertise to help develop solutions that could dramatically improve the lives of patients around the world.

“Pfizer’s goal with AWS is to accelerate drug discovery and development processes so that they can ultimately improve the patient experience and bring new therapies to market. By working closely with AWS experts in machine learning and analytics, we aim to provide our scientists and researchers with the information they need to help achieve life-changing medical breakthroughs, ”said Andrew McKillop , vice president of pharmaceutical, worldwide research, development, and medical sciences at Pfizer.

AWS is working with Pfizer to develop a prototype anomalous data point detection solution in its continuous clinical pharmaceutical manufacturing platform for solid oral dose drugs. The prototype solution uses Amazon SageMaker (an AWS service for building, training, and rapidly deploying machine learning models in the cloud and at the edge), Amazon Lookout for hardware, Amazon Lookout for metrics (the AWS service to automatically detect anomalies in metrics and identify their root cause) and Amazon QuickSight (AWS’s scalable business intelligence service for the cloud). The machine learning models used in the prototype were able to provide early alerts for alarms with minimal false positives and direct users to the relevant signals. As a result, Pfizer can process data from equipment and sensors involved in Miniature Continuous Portable and Modular (PCMM) to detect anomalies as they arise, forecast maintenance needs and reduce potential equipment downtime.

Pfizer scientists will also work with AWS healthcare and life science professionals to explore how researchers in Pfizer’s small molecule pharmaceutical science teams can extract and extract information from existing documents by leveraging analysis and machine learning services from AWS. Pfizer has an extensive collection of documents containing valuable data from various drug development processes. The documents include data relating to synthetic chemistry routes, recipes, analytical testing, method development, formulation composition, clinical manufacturing campaigns, batch registrations, technology transfer and development. many other types of work. These documents contain potentially powerful information that could point Pfizer researchers in the right direction to develop new drugs or reuse existing drugs, if researchers can effectively identify and link the right information. To gain fast, secure access to the right information at the right time, Pfizer’s small molecule pharmaceutical science teams are working with AWS to develop a prototype system that can automatically extract, ingest, and process data from this documentation to aid design. of the experiments laboratory. The prototype system is powered by Amazon Comprehend Medical (AWS’s HIPAA-eligible natural language processing (NLP) service for extracting information from unstructured medical text accurately and quickly) and Amazon SageMaker, and uses Amazon Cognito to provide secure user access control.

About Amazon Web Services

For more than 15 years, Amazon Web Services has been the most comprehensive and widely adopted cloud offering in the world. AWS has continuously expanded its services to support virtually any cloud workload, and now has more than 200 comprehensive services for compute, storage, databases, networking, l analysis, machine learning and artificial intelligence (AI), Internet of things (IoT), mobile, security, hybrid, virtual and augmented reality (VR and AR), development, deployment and management of media and d ” apps from 81 Availability Zones in 25 geographic regions, with plans announced for 27 additional Availability Zones and nine additional AWS Regions in Australia, Canada, India, Indonesia, Israel, New Zealand, Spain, Switzerland and the Arab Emirates United. Millions of customers, including the fastest growing startups, largest enterprises, and major government agencies, trust AWS to power their infrastructure, become more agile, and reduce costs. To learn more about AWS, visit aws.amazon.com.

About amazon

Amazon is guided by four principles: customer obsession rather than focus on competitors, passion for invention, commitment to operational excellence, and long-term thinking. Amazon strives to be the world’s most customer-centric company, the world’s best employer, and the world’s safest workplace. Customer Reviews, One-Click Purchases, Personalized Recommendations, Prime, Fulfillment by Amazon, AWS, Kindle Direct Publishing, Kindle, Career Choice, Fire Tablets, Fire TV, Amazon Echo, Alexa, Just Walk Out Technology, Amazon Studios and The Climate Pawnbrokers are some of the things that Amazon has come up with. For more information visit amazon.com/about and follow @AmazonNews.

About Pfizer: Advances That Change Patients’ Lives

At Pfizer, we apply science and our global resources to provide people with therapies that extend and dramatically improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health products, including innovative drugs and vaccines. Every day, Pfizer colleagues work in developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. In line with our responsibility as one of the world’s leading innovative biopharmaceutical companies, we collaborate with healthcare providers, governments and local communities to support and expand access to reliable and affordable healthcare in the whole world. For more than 170 years, we’ve worked to make a difference for all those who rely on us. We regularly post information that may be important to investors on our website at www.Pfizer.com. In addition, to find out more, visit us on www.Pfizer.com and follow us on Twitter at @Pfizer and @Pfizer News, LinkedIn, YouTube and like us on Facebook at Facebook.com/Pfizer.

Pfizer Disclosure Notice: The information in this press release is as of November 29, 2021. Pfizer assumes no obligation to update any forward-looking statements contained in this press release as a result of new information or future events or developments.

This release contains forward-looking information about an initiative between Amazon Web Services, Inc. (AWS) and Pfizer (the Pfizer Amazon Collaboration Team (PACT) initiative) that applies AWS capabilities in analytics, machine learning , compute, storage, security and cloud-based data warehousing at the Pfizer lab, clinical manufacturing and clinical supply chain efforts, including AWS and Pfizer’s efforts to create innovative solutions cloud-based technologies with the potential to improve the way new drugs are developed, manufactured and distributed for testing in clinical trials, including its potential benefits, which involve substantial risks and uncertainties that could result in actual results differ materially from those expressed or implied by such statements. Risks and uncertainties include, among others, uncertainties inherent in research and development; uncertainties regarding commercial success and the ability to realize the expected benefits of the initiative; uncertainties regarding the impact of COVID-19 on our business, operations and financial results; other trade effects, including effects of industry, market, economic, political or regulatory conditions; and competitive developments.

A more detailed description of the risks and uncertainties can be found in Pfizer’s annual report on Form 10-K for the year ended December 31, 2020 and in its subsequent reports on Form 10-Q, including in sections thereof. herein entitled “Risk Factors” and “Forward-Looking Information and Factors That May Affect Future Results”, as well as in its subsequent reports on Form 8-K, all of which are filed with the United States Securities and Exchange Commission and available at www.sec.gov and www.pfizer.com.


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