Shipment of GMP DMT, in vitro HERG and Genotox testing completed and in vivo toxicity testing in progress
Vancouver, British Columbia – (Newsfile Corp. – November 24, 2021) – Entheon Biomedical Corp. (CSE: ENBI) (OTCQB: ENTBF) (FSE: 1XU1) (“Entheon“or the”Society“), a biotechnology company focused on developing psychedelic drugs to treat addiction, is pleased to provide an update on its upcoming human trial, EBRX-101, and non-clinical DMT initiatives.
Update of clinical trials
The company announces today that the drug GMP DMT has been shipped from the Ofichem laboratory to the partner pharmacy of the CHDR. Formulation and stability testing of the DMT drug product by CHDR’s partner pharmacy has started according to the expected start date of EBRX-101, a study that will assess the pharmacodynamics, pharmacokinetics and safety of intravenous infusion. targeted N, N-dimethyltryptamine (“DMT”) in a population of healthy smokers.
Knowing that DMT has a favorable safety and toxicology profile based on historical preclinical and clinical research, Entheon embarked on several preclinical studies to further characterize the drug in support of Entheon’s specific clinical pathway and to meet the requirements for a future meeting with the FDA. As part of its non-clinical program, Entheon is pleased to announce that in vitro The HERG and genotox analyzes are completed, and in vivo Toxicity testing has started with final reports for the two studies due in the fourth quarter of 2021.
âThe Entheon science team is pleased to announce that the formulation and testing of the drug product DMT is currently underway for our next human trial. At the same time, we are making great progress with our preclinical toxicology program, which should strengthen the abundant safety data available in the published literature on DMT, âsaid Andrew Hegle, PhD, Scientific Director of Entheon.
About Entheon Biomedical Corp.
Entheon is a biotechnology research and development company engaged in the development and commercialization of a portfolio of safe and effective psychedelic therapeutics based on N, N-dimethyltryptamine (“DMT products“) for the purpose of treating substance abuse disorders. Subject to obtaining all required regulatory approvals and approvals, Entheon intends to generate revenue through the sale of its DMT products to physicians , clinics and licensed psychiatrists in the United States, some countries of the European Union and across Canada.
For more information, please contact the Company at:
Entheon Biomedical Corp.
Joseph Cullen, Investor Relations
Telephone: +1 (778) 919-8615
For media inquiries, please contact Elizabeth Glassen of BlueSky Communications at:
Elizabeth Glassen, Account Manager
Telephone: +1 (647) 309-0141
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